Yule Liu Ph.D.
Professor
1994-1997: Ph. D. Institute of Microbiology, Chinese Academy of Sciences, Beijing, China and Scottish Crop Research Institute, Dundee, UK
1990-1992: M. Sc. Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
1984-1988: B. Sc. Department of Biology, NanKai University, Tianjin, China
1988.8-1998.9: From Research Associate to Full Professor, Institute of Microbiology,
Chinese Academy of Sciences, Beijing, China
1995.5-1996.5: Visiting Scientist, Scottish Crop Research Institute, UK
1998.9-1999.8: Postdoc., University of Texas at Austin, TX, USA
1999.9-2002.8: Postdoc., Yale University, USA
2002.9-2006.12: Associate Research Scientist, Yale University, USA
2007.1 --- Professor, Tsinghua University, Beijing, China
Research interest
Signal transduction and regulation of plant immunity
Molecular basis of plant viral pathogenesis
Plant autophagy
Plant functional genomics
Selected publications
1. Yang M, Ismayil A, Jiang Z, Wang Y, Zheng X, Hong Y, Li D*, Liu Y*. A viral protein disrupts vacuolar acidification to facilitate virus infection in plants, EMBO Journal, 41(2): e108713, 2022
2. Wang Y, Gong Q, Wu Y, Huang F, Ismayil A, Zhang D, Li H, Gu H, Ludman M, Fátyol, Qi Y, Yoshioka K, Hanley-Bowdoin L, Hong Y, Liu Y*. A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants, Cell Host & Microbe 29, 1393–1406, 2021
3. Li H, Zhang D, Xie K, Wang Y, Liao Q, Hong H, Liu Y*. Efficient and high-throughput pseudorecombinant-chimeric Cucumber mosaic virus-based VIGS in maize. Plant Physiology, 187(4):2865-2876, 2021
4. Wang J, Chen T, Han M, Qian L, Li J, Wu M, Han T, Cao J, Nagalakshmi U, Rathjen JP, Hong Y, Liu Y*. Plant NLR immune receptor Tm-22 activation requires NB-ARC domain-mediated self-association of CC domain. PLoS Pathogens 16(4):e1008475, 2020
5. Ismayil A, Yang M, Haxima Y, Wang Y, Li J, Han L, Wang Y, Zheng X, Wei X, Nagalakshmi U, Hong Y, Hanley-Bowdoin L, Liu Y*. Cotton leaf curl Multan virus βC1 protein induces autophagy by disrupting the interaction of autophagy related protein 3 with Glyceraldehyde-3 Phosphate Dehydrogenases. Plant Cell 32(4):1124-1135, 2020
6. Ismayil A, Haxim Y, Wang Y, Li H, Qian L, Han T, Chen T, Jia Q, Yihao Liu A, Zhu S, Deng H, Gorovits R, Hong Y, Hanley-Bowdoin L, Liu Y*. Cotton Leaf Curl Multan virus C4 protein suppresses both transcriptional and post-transcriptional gene silencing by interacting with SAM synthetase. PLoS Pathogens 14(8): e1007282, 2018
7. Haxim Y, Ismayil A, Jia Q, Wang Y, Zheng X, Chen T, Qian L, Liu N, Wang Y, Han S, Cheng J, Qi Y, Hong Y, Liu Y*, Autophagy functions as an antiviral mechanism against geminiviruses in plants. eLife 6, e23897., 2017
8. Xu G, Wang S, Han S, Xie K, Wang Y, Li J, Liu Y*, Plant Bax Inhibitor-1 interacts with ATG6 to regulate autophagy and programmed cell death. Autophagy, 13(7):1161-1175, 2017
9. Jia Q, Liu N, Xie K, Dai Y, Han S, Zhao X, Qian L, Wang Y, Zhao J, Gorovits R, Xie D, Hong Y and Liu Y*, CLCuMuB βC1 Subverts Ubiquitination by Interacting with NbSKP1s to Enhance Geminivirus Infection in Nicotiana benthamiana, PLoS Pathogens, 12(6): e1005668, 2016
10. Wang Y, Zheng X, Yu B, Han S, Guo J, Tang H, Deng H, Hong Y and Liu Y*, Disruption of microtubules in plants suppresses macroautophagy and triggers starchy chloroplast autophagy, Autophagy 11(12): 2259-74, 2015
11. Han S，Wang Y, Zheng X, Jia Q, Zhao J, Bai F，Hong Y and Liu Y*, Cytoplastic glyceraldehyde-3-phosphate dehydrogenases interact with ATG3 to negatively regulate autophagy and immunity in Nicotiana benthamiana, Plant Cell 27(4):1316-31, 2015
12. Du Y, Zhao J, Chen T, Liu Q, Zhang H, Wang Y, Hong Y, Xiao F, Zhang L, Shen Q and Liu Y*, Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity, PLoS Pathogens, 9(10): e1003659, 2013.
13. Wang Y, Yu B, Zhao J, Guo J, Li Y, Han S, Huang L, Du Y, Hong Y, Tang D, and Liu Y*，Autophagy Contributes to the Leaf Starch Degradation, Plant Cell, 25(4): 1383-1399, 2013
14. Liu Y, Schiff M, Czymmek K, Talloczy Z., Levine B and Dinesh-kumar SP. Autophagy regulates programmed cell death during the plant innate immune response, Cell, 121(4), 567-577, 2005
15. Liu Y, Schiff M, Dinesh-Kumar S. P. Virus-induced gene silencing in Tomato, Plant Journal 31(6), 777-786, 2002
Contact information
Tel：+86-10-62794013
E-mail:yuleliu@mail.tsinghua.edu.cn
